Next, on this window select the tab ‘Compatibility’.This will launch a new window, that has the name ‘f4se_loader Properties’. After that, right-click on it and then, from the popup menu choose the option ‘Properties’. Now, within this folder, locate and then select the file “f4se_loader.exe”.By default, most of the time this folder can be present within “C:/Program Files/Fallout4”. First, locate the installation folder of the ‘Fallout 4’ game application.Follow the below mentioned steps, in order to achieve this. The best answer to solve this error is to run the built-in tool called ‘Compatibility Troubleshooter’.
Sometimes, due to some kind of conflict between the application ‘F4SE’ and the Windows Operating System, you might face the F4SE not working issue. Procedure to Execute the Compatibility Troubleshooter
Further, if the plugins are malfunctioning or are obsolete, then there is a possibility to encounter this issue. Even, if there is any kind of conflicts between the different modes of this game, then also this problem can crop up. Some of the most common ones are if the F4SE application is not up to date, then you can get this f4se not working error. There are various types of causes for this error. The F4SE is an application created by a community, which increases the capability of the game via a script. Even if the game opens then, it can crash all of a sudden. F4SE or Fallout 4 Script Extender can come up when you attempt to launch the game.